Pifithrin
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Pifithrin-α (chemical name 2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone hydrobromide[1]) is a chemical compound which acts as an inhibitor of the tumour-suppressing and epileptogenic protein p53.[2][3] It has a molecular weight of 367.30 and is soluble in DMSO up to 20 mg/mL. Its melting point is 192.1-192.5 °C.
References
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- ↑ George SL, Parmar V, Lorenzi F, Marshall LV, Jamin Y, Poon E, Angelini P, Chesler L. Novel therapeutic strategies targeting telomere maintenance mechanisms in high-risk neuroblastoma. J Exp Clin Cancer Res. 2020 May 6;39(1):78. Script error: No such module "CS1 identifiers". Template:Catalog lookup link
- ↑ Gupta V, Singh S, Singh TG. Pervasive expostulation of p53 gene promoting the precipitation of neurogenic convulsions: A journey in therapeutic advancements. Eur J Pharmacol. 2024 Nov 15;983:176990. Script error: No such module "CS1 identifiers". Template:Catalog lookup link
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