Philip Seeman
Template:Short description Script error: No such module "Unsubst". Script error: No such module "infobox".Script error: No such module "Check for unknown parameters".Script error: No such module "Check for clobbered parameters".Template:Wikidata image Philip Seeman, Template:Post-nominals (8 February 1934 – 9 January 2021) was a Canadian schizophrenia researcher and neuropharmacologist, known for his research on dopamine receptors.[1]
Career
Born in Winnipeg, Manitoba, Seeman was raised in Montreal. He received a Bachelor of Science degree, honours physics & physiology (1955), a Master of Science degree, physiology of transport & secretion (1956), and a Doctor of Medicine (1960) from McGill University. In 1966, he received a Ph.D. in life sciences from Rockefeller University under the supervision of George Emil Palade.[2]
In 1967, Seeman became an assistant professor in the Department of Pharmacology at the University of Toronto. In 1970, he was appointed a professor.
In 1974, having spent years in search of the binding site of antipsychotic medication, he discovered the dopamine D2 receptor, the basis for the dopamine hypothesis of schizophrenia.[3][4] His discoveries also helped advance research on other diseases involving dopamine, such as Parkinson's disease and Huntington's disease.[2]
In 1985, he was made a Fellow of the Royal Society of Canada.[5]
In 2001, he was made an Officer of the Order of Canada "for his research on dopamine receptors and their involvement in diseases such as schizophrenia, Parkinson's and Huntington's".[6]
He was married to Dr. Mary V. Seeman.[7]
Notes
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References
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- P. Seeman (2010). "Dopamine D2 Receptors as Treatment Targets in Schizophrenia. Clinical Schizophrenia & Related Psychoses April: 56-73.
- P. Seeman (2007), Scholarpedia, 2(10): 3634 doi.4249/scholarpedia.3634
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External links
- Home Page of Philip Seeman's Laboratory
- Probing the Biology of Psychosis, Schizophrenia, and Antipsychotics: An Expert Interview With Dr. Philip Seeman, MD, PhD – an interview on the Medscape website
- Schizophrenia – an essay by Philip Seeman, November 2001