Phenylglyoxylic acid

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Phenylglyoxylic acid
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Molar mass 150.13 g/mol
Appearance colorless solid
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Phenylglyoxylic acid is the organic compound with the formula C6H5C(O)CO2H. The conjugate base, known as benzoylformate is the substrate of benzoylformate decarboxylase, a thiamine diphosphate-dependent enzyme:

benzoylformate + H+benzaldehyde + CO2

It is a colourless solid with a melting point of 64–66 °C and is moderately acidic (pKa = 2.15).

Phenylglyoxylic acid can be synthesized by oxidation of mandelic acid with potassium permanganate.[1] An alternative synthesis involves hydrolysis of benzoyl cyanide.[2]

References

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