Perfluoropentane
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| Template:Longitem | 1712388 |
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| Molar mass | Template:Chem molar mass |
| Density | 1.63 g/mL (liquid, 25 °C)[2] 1.59 g/mL (liquid, 35 °C) 12.25 kg/m³ (gas, 1 atm, 10 times air density) |
| Melting point | Template:Chembox CalcTemperatures |
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| Vapor pressure | 83.99 kPa (25 °C) |
| Viscosity | 0.652 mPa*s (25 °C) |
| Template:Longitem | 0.26 cal/(g • K) |
| Template:Longitem | V08DA03 (WHO) |
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Perfluoropentane (PFP) or dodecafluoropentane; also known as Perflenapent (INN/USAN) is a fluorocarbon, the fluorinated analogue of pentane. It is a liquid that boils at slightly over room temperature.
It has several biomedical applications including: propellant for pressurized metered dose inhalers;[3] gas core in microbubble ultrasound contrast agents;[4] and occlusion therapy via the conversion of nanometer liquid droplets into micrometer sized gas microbubbles (acoustic droplet vaporization).[5]
References
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- ↑ Rogueda, P. G. A. HPFP, a Model Propellant for pMDIs. Drug Dev. Ind. Phar. 2003, 29, 39
- ↑ Liu, Y., Miyoshi, H., and Nakamura, M. Encapsulated ultrasound microbubbles: Therapeutic application in drug/gene delivery. J. Controlled Release 2006, 114, 89− 99
- ↑ D. Bardin, T. D. Martz, P. S. Sheeran, R. Shih, P. A. Dayton, and A. P. Lee, “High-speed, clinical-scale microfluidic generation of stable phase-change droplets for gas embolotherapy,” Lab on a Chip, vol. 11, no. 23, p. 3990, 2011.
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