Passenger leukocyte

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Template:Short description In tissue and organ transplantation, the passenger leukocyte theory is the proposition that leucocytes within a transplanted allograft sensitize the recipient's alloreactive T-lymphocytes, causing transplant rejection.[1]

The concept was first proposed by George Davis Snell[2] and the term coined in 1968 when Elkins and Guttmann showed that leukocytes present in a donor graft initiate an immune response in the recipient of a transplant.[3]

See also

References

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Further reading

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