PTF

• Palomar Transient Factory, an astronomical survey program
• Pedotransfer function, a concept used in soil science
• Phase transfer function, used for the optics of an imaging system

Computing

• Program temporary fix (PTF file format), an IBM locution to designate bug fixes
• PlayStation Portable, a file extension for the PlayStation Portable systems
• Pro Tools 7 up to Pro Tools 9 session (project) file

Other

• Pat Tillman Foundation, a scholarship and leadership nonprofit serving U.S. military veterans and military spouses
• Peter Tatchell Foundation, a British human rights organization
• Police Task Force, former name of the Police Tactical Unit of the Singapore Police Force
• Präzisionsteilefertigung Steffen Pfüller, a producer of high-tech precision parts and assemblies
• PTF boat a type of Patrol Craft used in Vietnam