PHF1

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Template:Short description Template:Infobox gene PHD finger protein 1 is a protein that in humans is encoded by the PHF1 gene.[1][2][3]

Function

This gene encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. Two transcript variants have been found for this gene.[3]

References

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Further reading

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External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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