PHACTR3

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Template:Short description Template:Infobox gene Phosphatase and actin regulator 3 is an enzyme that in humans is encoded by the PHACTR3 gene.[1][2]

Function

The protein encoded by this gene is associated with the nuclear scaffold in proliferating cells. It was found to bind to the catalytic subunit of protein phosphatase-1 (PP1) and inhibit PP1 activity, suggesting that this protein may function as a regulatory subunit of PP1. Alternative splicing at this locus results in several transcript variants encoding different isoforms.[2]

Interactions

PHACTR3 has been shown to interact with PPP1CA.[3]

References

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Further reading

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