PFDN5
Template:Short description Template:Infobox gene Prefoldin subunit 5 is a protein that in humans is encoded by the PFDN5 gene.[1][2][3]
This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described.[3]
Interactions
PFDN5 has been shown to interact with Myc.[2][4]
References
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Further reading
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