PEX16

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Template:Short description Template:Infobox gene Peroxisomal membrane protein PEX16 is a protein that in humans is encoded by the PEX16 gene.[1][2]

Function

The protein encoded by this gene is an integral peroxisomal membrane protein. An inactivating nonsense mutation localized to this gene was observed in a patient with Zellweger syndrome of the complementation group CGD/CG9. Expression of this gene product morphologically and biochemically restores the formation of new peroxisomes, suggesting a role in peroxisome organization and biogenesis. Alternative splicing has been observed for this gene and two variants have been described.[2]

Interactions

PEX16 has been shown to interact with PEX19.[3]

References

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Further reading

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External links


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