P2RY8

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Template:Short description Template:Infobox gene P2Y purinoceptor 8 is a protein that in humans is encoded by the P2RY8 gene.[1][2]

Function

The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y.[2]

Clinical relevance

Recurrent mutations in this gene have been associated to cases of diffuse large B-cell lymphoma.[3]

See also

References

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Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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