p-Anisic acid
p-Anisic acid, also known as 4-methoxybenzoic acid or draconic acid, is one of the isomers of anisic acid. The term "anisic acid" often refers to this form specifically.[1] It is a white crystalline solid which is insoluble in water, highly soluble in alcohols, and soluble in ether and ethyl acetate.[1]
Synthesis and occurrence
p-Anisic acid is found naturally in anise.Template:Source? It was first synthesized in 1841 by Auguste Cahours by oxidizing anethole that he had isolated from anise by recrystallization with diluted nitric acid:[2][3]
Oxidation of anisaldehyde, which was Cahours' intermediate product, is still used nowadays.[4] Anisic acid can also be obtained synthetically by the oxidation of p-methoxyacetophenone.
Uses
p-Anisic acid has antiseptic properties.[5] It is also used as an intermediate in the preparation of more complex organic compounds.
References
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