Oxalate decarboxylase

Template:Infobox enzyme In enzymology, an oxalate decarboxylase (Template:EnzExplorer) is an oxalate degrading enzyme that catalyzes the chemical reaction

oxalate + H⁺ $\rightleftharpoons$ formate + CO₂

Thus, the two substrates of this enzyme are oxalate and H⁺, whereas its two products are formate and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is oxalate carboxy-lyase (formate-forming). This enzyme is also called oxalate carboxy-lyase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

Structural studies

As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes 1UW8, 2UY8, 2UY9, 2UYA, and 2UYB.

References

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