Neuroserpin

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Template:Cs1 config Template:Short description Template:Infobox gene Neuroserpin is a protein that in humans is encoded by the SERPINI1 gene.[1]

It is associated with Familial encephalopathy with neuroserpin inclusion bodies.

Serine protease inhibitors of the serpin superfamily are involved in many cellular processes. Neuroserpin was first identified as a protein secreted from the axons of dorsal root ganglion neurons (Stoeckli et al., 1989). It is expressed in the late stages of neurogenesis during the process of synapse formation.[supplied by OMIM][1]

Interactions

SERPINI1 has been shown to interact with Tissue plasminogen activator.[2]

References

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Further reading

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External links

  • The MEROPS online database for peptidases and their inhibitors: I04.025

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