NCOA4
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Template:Short description Template:Infobox gene Nuclear receptor coactivator 4, also known as Androgen Receptor Activator (ARA70), is a protein that in humans is encoded by the NCOA4 gene.[1][2][3] It plays an important role in ferritinophagy, acting as a cargo receptor, binding to the ferritin heavy chain and latching on to ATG8 on the surface of the autophagosome.
Interactions
NCOA4 has been shown to interact with:
- Androgen receptor,[2][4][5][6][7][8][9][10][11] and
- Peroxisome proliferator-activated receptor gamma[12]
- Ferritin[13][14]
- ATG8[15]
See also
References
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Further reading
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External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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