Mycobacterium intermedium
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Mycobacterium intermedium is a species of the phylum Actinomycetota (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus Mycobacterium.
Etymology: Latin; intermedium, meaning between, rapidly and slowly growing mycobacteria.
Description
Gram-positive, and nonmotile acid-fast coccobacilli (2.0 μm x 2.6 μm).
Colony characteristics
- Eugonic, smooth and photochromogenic colonies (3–5mm in diameter) on Löwenstein-Jensen medium.
Physiology
- Growth on Löwenstein-Jensen medium at 22 °C, 31 °C, 37 °C and 41 °C, (optimal temperature between 31 °C and 37 °C), within 2–3 weeks.
- Susceptible to ethambutol and rifampin.
- Resistant to isoniazid and streptomycin.
Differential characteristics
- Phylogenetic position between rapidly and slowly growing mycobacteria.
- M. asiaticum is phenotypically very similar, but can be distinguished by its growth at 22 °C, and by its dysgonic growth.
Pathogenesis
- Pulmonary disease
- Biosafety level 2
Type strain
- Repeatedly isolated from sputum from a patient with pulmonary disease.
Strain 1669/91 = ATCC 51848 = CCUG 37583 = CIP 104542 = DSM 44049 = JCM 13572
References
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- Meier et al. 1993. Mycobacterium intermedium sp. nov. Int. J. Syst. Bacteriol., 1993, 43, 204–209.