Mogroside

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Template:Short description

File:Mogroside II E.svg
Structural formula of mogroside 2 E

A mogroside is a triterpene glycoside of cucurbitane derivatives found in certain plants, such as the fruit of the gourd vine Siraitia grosvenorii (known as monkfruit or luohan guo).[1][2] Mogrosides are extracted from S. grosvenorii and used in the manufacture of sugar substitutes.[1][2]

Mogrosides

File:Mogrosid V.svg
Structural formula of mogroside V
File:Mogroside VI.svg
Structural formula of mogroside VI

Mogrosides include:[1][2]Template:Not in citation givenScript error: No such module "Unsubst".

The total content of mogrosides in Siraitia grosvenorii fruit is 3.8% with Mogroside V having the highest content (0.8% to 1.3% w/w).[3]

Biosynthesis

One analysis of 200 candidate genes of Siraitia grosvenorii revealed five enzyme families involved in the synthesis of mogroside V: squalene epoxidases, triterpenoid synthases, epoxide hydrolases, cytochrome P450s, and UDP-glucosyltransferases.[1] The metabolic pathway for mogroside biosynthesis involves an initial stage of fruit development when squalene is metabolized to di-glucosylated, tetra-hydroxycucurbitadienols, then during fruit maturation, branched glucosyl groups are added and catalyzed, leading to the sweet M4, M5, and M6 mogrosides.[1]

Stability

Mogroside V appears to be heat stable in the range of 100 to 150 degrees Celsius for 4 hours and up to 8 hours in boiling water. It is stable at a pH of between 3 and 12 when stored from 2 to 8 degrees Celsius.[4]

Uses

Some mogrosides are used in traditional Chinese medicine[2] and some are extracted for manufacturing as sweeteners.[1] Mogroside V extract from S. grosvenorii fruit is 250 times sweeter than sucrose,[1] sold commercially in Norbu (sweetener).

References

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External links

  1. a b c d e f g Script error: No such module "Citation/CS1".
  2. a b c d Subhuti Dharmananda (January 2004), "Luo han guo - Sweet fruit used as sugar substitute and medicinal herb". Institute for Traditional Medicine, Portland, Oregon.
  3. Script error: No such module "Citation/CS1".
  4. Script error: No such module "Citation/CS1".