Miotine
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Miotine is an anticholinesterase drug. Miotine was the first synthetic carbamate that was used clinically.[1]
Unlike the miotine analog neostigmine, it doesn't have a quaternary ammonium group to give it a permanent positive charge. It can exist as an uncharged free base which could allow it to cross the blood–brain barrier and cause unwanted central nervous system (CNS) side effects.[2]
Miotine equilibrium Miotine equilibrium
