Methyl chloroformate
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| Template:Longitem | 605437 |
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| Template:Longitem | Template:Chem2 |
| Molar mass | Template:Chem molar mass |
| Appearance | Colorless oily liquid |
| Odor | Pungent |
| Density | 1.223 g/mL |
| Boiling point | Template:Chembox CalcTemperatures |
| Flash point | Template:Chembox CalcTemperatures |
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Methyl chloroformate is a chemical compound with the chemical formula Template:Chem2. It is the methyl ester of chloroformic acid. It is an oily colorless liquid, although aged samples appear yellow. It is also known for its pungent odor.
Preparation
Methyl chloroformate can be synthesized using anhydrous methanol and phosgene.[2]
Properties
Methyl chloroformate hydrolyzes in water to form methanol, hydrochloric acid, and carbon dioxide.[3] This decomposition happens violently in the presence of steam, causing foaming. The compound decomposes in heat, which can liberate hydrogen chloride, phosgene, chlorine, or other toxic gases.[4]
Uses
Methyl chloroformate is used in organic synthesis for the introduction of the methoxycarbonyl functionality to a suitable nucleophile (i.e. carbomethoxylation).[5]
Safety
Methyl chloroformate forms highly flammable vapour-air mixtures. The compound has a flash point of 10 °C.[6] Methyl chloroformate, if heated, releases phosgene. It produces hydrogen chloride upon contact with water. It will cause skin damage if in contact with skin.
See also
References
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- ↑ Methyl chloroformate at Sigma-Aldrich
- ↑ Siegfried Böhm, Maren Beth-Hübner: Chloroformic Esters. In: Ullmann’s Encyclopedia of Industrial Chemistry. Wiley‐VCH Verlag GmbH & Co. KGaA., 15. April 2006, Script error: No such module "CS1 identifiers"..
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- ↑ E. Brandes, W. Möller: Sicherheitstechnische Kenngrößen. Band 1: Brennbare Flüssigkeiten und Gase. Wirtschaftsverlag NW – Verlag für neue Wissenschaft, Bremerhaven 2003.
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