Methorphan
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Methorphan is an opioid drug that occurs in two isomeric forms, each with differing pharmacology and effects:
- DextromethorphanTemplate:Snd An over-the-counter cough suppressant, as well as dissociative hallucinogen.
- LevomethorphanTemplate:Snd A potent opioid analgesic that was never clinically developed; a prodrug of the powerful opioid agonist analgesic levorphanol (Levo-Dromoran).
Racemethorphan is the racemic mixture of both of these stereoisomers.[1] It is listed under the Single Convention on Narcotic Drugs 1961 and is therefore listed in the United States as a Controlled Substance, specifically as a Narcotic in Schedule II with an ACSCN of 9732 and an annual aggregate manufacturing quota of 3 grams in 2014.[2][3] The salts in use are the hydrobromide (free base conversion ratio 0.770) and the tartrate (0.644).
See also
References
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