Metharbital

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Metharbital was patented in 1905 by Emil Fischer working for Merck.[1] It was marketed as Gemonil by Abbott Laboratories. It is a barbiturate anticonvulsant, used in the treatment of epilepsy.[2][3] It has similar properties to phenobarbital.

History

  • 1952 Gemonil was introduced by Abbott Laboratories.
  • 1990 Abbott stopped marketing.

Synthesis

Metharbital can be synthesized from 2,2-diethylmalonic acid and O-methylisourea.[4][5][1]

References

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  1. ↑ a b <templatestyles src="Citation/styles.css"/>Template:Citation/make link, Fischer E, "Trisubstituted barbituric acids and process of making them.", issued Script error: No such module "auto date formatter"., assigned to E. Merck Script error: No such module "Check for unknown parameters".
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