Mark B. Gerstein
Template:Short description Script error: No such module "Template wrapper".Script error: No such module "Check for clobbered parameters". Mark Bender Gerstein is an American scientist working in bioinformatics and data science. As of 2009[update]Script error: No such module "Check for unknown parameters"., he is co-director of the Yale Computational Biology and Bioinformatics program.
Mark Gerstein is Albert L. Williams Professor of Biomedical Informatics, professor of molecular biophysics & biochemistry, professor of statistics & data science, and professor of computer science at Yale University.[1] In 2018, Gerstein was named co-director of the Yale Center for Biomedical Data Science.[2]
Education
After graduating from Harvard College summa cum laude with a Bachelor of Arts in physics in 1989, Gerstein did a PhD co-supervised by Ruth Lynden-Bell[3] at the University of Cambridge and Cyrus Chothia at the Laboratory of Molecular Biology on conformational change in proteins, graduating in 1993.[4] He then went on to postdoctoral research in bioinformatics at Stanford University from 1993 to 1996 supervised by Nobel-laureate Michael Levitt.
Research
Gerstein does research in the field of bioinformatics.[5][6][7] This involves applying a range of computational approaches to problems in molecular biology, including data mining and machine learning, molecular simulation, and database design. His research group has a number of foci including annotating the human genome,[8] personal genomics, cancer genomics, building tools in support of genome technologies (such as next-generation sequencing), analyzing molecular networks, and simulating macromolecular motions. Notable databases and tools that the group has developed include the Database of Macromolecular Motions,[9][10] which categorizes macromolecular conformational change; tYNA,[11] which helps analyze molecular networks; PubNet,[12] which analyzes publication networks; PeakSeq,[13] which identifies regions in the genome bound by particular transcription factors; and CNVnator,[14] which categorizes block variants in the genome. Gerstein has also written extensively on how general issues in data science impact on genomics—in particular, in relation to privacy[15] and to structuring scientific communication.[16]
Gerstein's work has been published in peer reviewed scientific journals[17][18][19] and non-scientific publications in more popular forums.[20] His work has been highly cited, with an H greater than 100.[5] He serves on a number of editorial and advisory boards, including those of PLoS Computational Biology, Genome Research, Genome Biology, and Molecular Systems Biology. He has been quoted in the New York Times,[21][22][23] including on the front page,[8] and in other major newspapers.[24]
Awards and honors
In addition to a W. M. Keck Foundation Distinguished Young Scholars award,[25] Gerstein has received awards from the US Navy, IBM, Pharmaceutical Research and Manufacturers of America, and the Donaghue Foundation.[26] He is a Fellow of the AAAS.[27] Other awards include a Herchel-Smith Scholarship supporting his doctoral work at Emmanuel College, Cambridge and a Damon Runyon Cancer Research Foundation Postdoctoral Fellowship. He is a contributor to a number of scientific consortia including ENCODE,[28] modENCODE,[29][30][31] 1000 Genomes Project, Brainspan,[32] and DOE Kbase.Script error: No such module "Unsubst". He was made a Fellow of the International Society for Computational Biology in 2015.[33]
References
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- ↑ a b Gina Kolata, (Sept. 5, 2012) 'Bits of Mystery DNA, Far From Junk, Play Crucial Role,' NY Times
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External links
- Mark Gerstein Laboratory at Yale
- Mark Gerstein at Yale Computer Science
- Mark Gerstein at Yale School of Medicine
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- Mark Gerstein publications on ResearchGate
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- Pages with script errors
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- 21st-century American biologists
- American bioinformaticians
- Harvard College alumni
- Stanford University alumni
- Living people
- Yale University faculty
- Fellows of the International Society for Computational Biology
- Fellows of the American Association for the Advancement of Science
- Alumni of Emmanuel College, Cambridge
- Yale Department of Molecular Biophysics & Biochemistry faculty