MHC class I polypeptide–related sequence B
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Template:Short description Template:Cs1 config Template:Infobox gene MHC class I polypeptide-related sequence B (MICB) is a protein that is encoded by the MICB gene located within MHC locus.[1] MICB is related to MHC class I and has similar domain structure, which is made up of external α1α2α3 domain, transmembrane segment and C-terminal cytoplasmic tail.[1] MICB is a stress-induced ligand for NKG2D receptor.[2] The heat shock stress pathway is involved in the regulation of MICB expression as transcription of MICB is regulated by promoter heat shock element.[3]
See also
References
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Further reading
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