MARCH2
Template:Short description Template:Cs1 config Template:Infobox gene E3 ubiquitin-protein ligase MARCH2 is an enzyme that in humans is encoded by the MARCH2 gene.[1][2][3] It is a member of the MARCH family of E3 ligases, and plays an important role in the turnover of membrane proteins.[4] MARCH2 has been shown to negatively regulate NF-κB essential modulator function upon viral and bacterial infections.[5]
Gene name error in Excel
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Like the other MARCH and septin genes, care must be exercised when analyzing genetic data containing the MARCH2 gene in Microsoft Excel.[6] This is due to Excel's autocorrect feature treating the MARCH gene as a date and converting it to a standard date format. The original text cannot be recovered as a result of the conversion. A 2016 study found up to 19.6% of all papers in selected journals to be affected by the gene name error.[7] The issue can be prevented by using an alias name such as MARCHF2, prepending with an apostrophe ('), or preformatting the cell as text.
References
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Further reading
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