MAD2L2

Template:Cs1 config Template:Short description Template:Infobox gene Mitotic spindle assembly checkpoint protein MAD2B is a protein that in humans is encoded by the MAD2L2 gene.

Function

MAD2L2 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L2 is a homolog of MAD2L1.

Interactions

MAD2L2 has been shown to interact with:

• ADAM9,
• MAD2L1,
• REV1, and
• REV3L.