Lysophosphatidylserine
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Template:Short description A lysophosphatidylserine is a lysophospholipid. Various lysophosphatidylserines trigger TLR 2.[1] They can also modulate T cell function via suppression of Interleukin_2 (IL-2) production in CD4 T cells.[2] They can also trigger mast cell degranulation.[3] They interact with three G protein-coupled receptors (GPCRs), LPS1/GPR34, LPS2/P2Y10, and LPS3/GPR174.[2]
A recent study showed that lysophosphatidylserines do not stimulate normal leukocytes.[4] They also enhances glucose transport, lowering blood glucose levels while leaving secretion of insulin unaffected.[5]