List of highways numbered 421

The following highways are numbered 421:

Canada

• Manitoba Provincial Road 421
• Newfoundland and Labrador Route 421

Japan

• File:Japanese National Route Sign 0421.svg Japan National Route 421

United States

• File:US 421.svg U.S. Route 421
• File:Florida 421.svg Florida State Road 421
  • File:Volusia County 421.svg County Road 421 (Volusia County, Florida)
• File:Georgia 421.svg Georgia State Route 421 (unsigned designation for Interstate 516)
• File:New Mexico 421.svg New Mexico State Road 421
• File:NY-421.svg New York State Route 421
• File:OH-421.svg Ohio State Route 421
• File:Ellipse sign 421.svg Puerto Rico Highway 421
• File:South Carolina 421.svg South Carolina Highway 421
• File:Secondary Tennessee 421.svg Tennessee State Route 421
• File:Texas Spur 421.svg Texas State Highway Spur 421

Preceded by 420

Lists of highways 421

Succeeded by 422