L-arabinose isomerase
Template:Infobox enzyme Template:Short description
Script error: No such module "Infobox".Template:Template other In enzymology, a L-arabinose isomerase (Template:EnzExplorer) is an enzyme that catalyzes the chemical reaction
- L-arabinose L-ribulose
Hence, this enzyme has one substrate, L-arabinose, and one product, L-ribulose.
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is L-arabinose aldose-ketose-isomerase. This enzyme participates in pentose and glucuronate interconversions.
This enzyme catalyses the conversion of L-arabinose to L-ribulose as the first step in the pathway of L-arabinose utilization as a carbon source.[1]
Industrial applications
In 1993, scientists discovered that L-arabinose isomerase from the bacterium Lactobacillus gayonii can convert D-Galactose to D-Tagatose.[2] Tagatose is a biologically rare sugar that has been explored as an alternative sweetening agent in foods due to its low glycemic index.[3][4] L-arabinose isomerase has been explored as a biological method for producing this sugar industrially.[5]
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2AJT and 2HXG.
References
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- ↑ <templatestyles src="Citation/styles.css"/>Template:Citation/make link, Ibrahim, Osama O. & Spradlin, Joseph E., "D-tagatose production by enzymatic isomerization of D-galactose", issued Script error: No such module "auto date formatter".Script error: No such module "Check for unknown parameters".
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Further reading
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