K+-transporting ATPase
In enzymology, a K+-transporting ATPase (EC 3.6.3.12) is an enzyme that catalyzes the chemical reaction
- ATP + H2O + K+out Template:Eqm ADP + phosphate + K+in
The 3 substrates of this enzyme are ATP, H2O, and K+, whereas its 3 products are ADP, phosphate, and K+.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (K+-importing). Other names in common use include K+-translocating Kdp-ATPase, and multi-subunit K+-transport ATPase. This enzyme participates in two-component system - general.
Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 1SVJ, 1U7Q, 2A00, and 2A29.
References
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