Isogenous group
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An isogenous group (lat. "equal origin") is a cluster of up to eight chondrocytes[1] found in hyaline and elastic cartilage.[2]
Formation
Chondrocytes develop in the embryo from mesenchymal progenitor cells through a process known as chondrogenesis.[2][3] A chondrocyte can then undergo mitosis to form an isogenous group within its lacuna.[3][4]
Function
Isogenous groups differentiate into individual chondrocytes where they continue to produce and deposit extracellular matrix (ECM), lengthening the cartilage and increasing its diameter.[3][5] This is termed interstitial growth and is one of only two ways cartilage can grow.[4]
