Hydroxymandelonitrile lyase

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Template:Short description Template:Infobox enzyme In enzymology, a hydroxymandelonitrile lyase (Template:EnzExplorer) is an enzyme that catalyzes the chemical reaction

(S)-4-hydroxymandelonitrile cyanide + 4-hydroxybenzaldehyde

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (S)-4-hydroxymandelonitrile 4-hydroxybenzaldehyde-lyase (cyanide-forming). Other names in common use include hydroxynitrile lyase, oxynitrilase, Sorghum hydroxynitrile lyase, and (S)-4-hydroxymandelonitrile hydroxybenzaldehyde-lyase. This enzyme participates in cyanoamino acid metabolism.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1GXS.

References

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