Herpes simplex virus protein vmw65
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Template:Pfam box Vmw65, also known as VP16 or α-TIF (Trans Inducing Factor)[1] is a trans-acting protein that forms a complex with the host transcription factors Oct-1 and HCF to induce immediate early gene transcription in the herpes simplex viruses.[2][3]
VP16 is a strong transactivator[4] and is often used in Y2H systems as the activation domain of the system.[5]
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