H antigen
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Template:Short description Script error: No such module "redirect hatnote". H antigen can refer to one of the various types of antigens having diverse biological functions:
- Also known as substance H, H antigen is a precursor to each of the ABO blood group antigens, apparently present in all people except those with the Bombay Blood phenotype[1] (see hh blood group). The gene responsible for making H antigen is FUT1, located on the 19th chromosome in humans.
- Histocompatibility antigen, a major factor in graft rejection. Even when Major Histocompatibility Complex genotype is perfectly matched, can cause slow rejection of a graft.[2]
- major H antigens "encode molecules that present foreign peptides to T cells"[2]
- minor H antigens "present polymorphic self peptides to T cells".[2] Includes, e.g. the H-Y antigen
- a bacterial flagellar antigen[3]
References
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