HLA-Cw4

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HLA-Cw4 (Cw4) is a human leukocyte antigen serotype within HLA-C serotype group. (For more general information on HLA serotypes, please see the article: History and naming of human leukocyte antigens.) Cw4 is determined by the antibody recognition of α4 subset of HLA-Cw α-chains. For the serotype Cw4, the alpha chain are encoded by the HLA-Cw<templatestyles src="Template:Color/styles.css" />*04 allele group and the β-chain are encoded by B2M locus.[1] Cw4 and Cw<templatestyles src="Template:Color/styles.css" />*04 are almost synonymous in meaning. Cw4 is more common in Southeast Europe, where it is part of the Cw4-B35 haplotype.

Serotype

Cw4 recognition of some HLA Cw*04 gene products[2]
Cw*04 Cw4 Cw403 Cw<templatestyles src="Template:Color/styles.css" />6 Sample
allele % % % size (N)
*0401 98 0 0 736
*0403 37 5 <templatestyles src="Template:Color/styles.css" />17 25


Alleles

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References

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  2. Allele Query Form IMGT/HLA - European Bioinformatics Institute

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