HLA-B67

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Template:Short description

major histocompatibility complex (human), class I, B67
Alleles B*6701
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*6701
Locus chr.6 6p21.31

HLA-B67 (B67) is an HLA-B serotype. The serotype identifies the more common HLA-B*67 gene products.[1] B67 is region specific recombinant haplotype formed by the gene conversion of B*39, an allele common along the Northwest Pacific Rim (Taiwan, Japan, Korea, Coastal Siberia), and B7, B22, or B27.[2] (For terminology help see: HLA-serotype tutorial)

Serotype

B67 Serotype recognition of the B*67 allele-group gene products[3]
B*67 B67 Other Sample
allele % % size (N)
6701 32 62 81

By allele

Regions of higher B*6701 frequency
Japan File:LocationJapan.svg
Taiwan File:LocationTaiwan.svg
Heilongjiang
province, China
(Harbin city)
File:China-Heilongjiang.png
Beijing
China
File:China-Beijing.png
Shandong
peninsula
File:Location-of-Shandong-Peninsula.png
HLA B*6701 frequencies
freq
ref. Population (%)
[4] Osaka Region (Japan) 2.6
[4] Hakka (Taiwan) 1.8
[4] Japan (5) 1.7
[4] Harbin Man (China) 1.7
[4] Beijing (China) 1.5
[4] Linqu (Shandong, China) 1.1
[4] Siraya (Taiwan) 1.0
[4] Portugal South 1.0
[4] Oold (Mongolia) 1.0
[4] American Samoa 1.0
[4] Pazeh (Taiwan) 0.9
[4] South Korea (3) 0.9
[4] N. Korean (Harbin, China) 0.8
[4] Arratia Basque (Spain) 0.6
[4] Tarialan Khoton (Mongolia) 0.6
[4] Shanghai (China) 0.6
[4] Natal Zulu (South African) 0.5
[4] Yunnan Han (China) 0.5
[4] Turkey 0.4
[4] Southern Han (China) 0.4
[4] Tuva (Russia) 0.3
[4] Chinese (Hong Kong, China) 0.1

References

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  3. derived from IMGT/HLA
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