HLA-B50

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Template:Short description

major histocompatibility complex (human), class I, B50
Alleles B*5001, B*5002,
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*5001
B*5002
Locus chr.6 6p21.31

HLA-B50 (B50) is an HLA-B serotype. B50 is a split antigen from the B21 broad antigen, the sister serotype B49.[1] The serotype identifies the more common HLA-B*50 gene products.[2] (For terminology help see: HLA-serotype tutorial)

Serotype

B50 and B21 serotype recognition of some more common HLA B*50 alleles[3]
B*50 B50 B21 Sample
allele % % size (N)
5001 85 3 1700

The B*5002 by serotype definition is a B45 serotype.[4]

Allele distribution

HLA B*5001 frequencies
freq
ref. Population (%)
[5] Saudi Arabia Guraiat and Hail 17.3
[5] Tunisia 10.0
[5] Israel Arab Druse 8.5
[5] Morocco Nador Metalsa (Berber) 7.3
[5] Tunisia Tunis 6.3
[5] Israel Ashkenazi and Non Ashkenazi Jews 5.5
[5] Azores Terceira Island 5.1
[5] Georgia Svaneti Svans 3.8
[5] India North Delhi 3.8
[5] Italy Bergamo 3.6
[5] Georgia Tbilisi Kurds 3.4
[5] Italy North (1) 3.3
[5] Brazil Belo Horizonte 3.2
[5] Madeira 3.2
[5] Italy North Pavia 3.1
[5] Portugal South 3.1
[5] Oman 3.0
[5] Georgia Tbilisi Georgians 2.8
[5] Bulgaria 2.7
[5] Azores Santa Maria and Sao Miguel 2.6
[5] Spain Eastern Andalusia Gipsy 2.5
[5] Sudanese 2.5
[5] Czech Republic 2.4
[5] Spain Eastern Andalusia 2.4
[5] Spain Mallorca and Menorca 2.2
[5] Burkina Faso Fulani 2.0
[5] China Inner Mongolia 2.0
[5] China North Han 1.9
[5] India North Hindus 1.9
[5] China Qinghai Hui 1.8
[5] Jordan Amman 1.7
[5] Russia Tuva (2) 1.7
[5] Spain Catalonia Girona 1.7
[5] Senegal Niokholo Mandenka 1.6
[5] Guinea Bissau 1.5
[5] India New Delhi 1.5
[5] Croatia 1.3
[5] Cuban Mulatto 1.2
[5] France South East 1.2
[5] Burkina Faso Rimaibe 1.1
[5] Mali Bandiagara 1.1
[5] Belgium 1.0
[5] Ireland Northern 1.0
[5] Ireland South 1.0
[5] Italy Sardinia pop3 1.0
[5] South Africa Natal Tamil 1.0
B*5002
[5] Morocco Nador Metalsa (Berber) 4.3
[5] Portugal North 1.1
[5] Portugal South 1.0
[5] Madeira 0.8
[5] Tunisia Tunis 0.6

References

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