HLA-B35
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| Computer illustration of HLA-B*3508 with EBV (EPLPQGQLTAY) in the binding pocket. | ||
| B*3508-β2MG with bound peptide | ||
| Template:PDB2 | ||
major histocompatibility complex (human), class I, B35
| ||
| Alleles | B*3501, 3502, 3503, . . . | |
| Structure (See HLA-B) | ||
| Symbol(s) | HLA-B | Template:PDB2, Template:PDB2 |
| EBI-HLA | B*3501 | Template:PDB2, Template:PDB2, Template:PDB2 |
| EBI-HLA | B*3502 | |
| EBI-HLA | B*3503 | |
| EBI-HLA | B*3504 | |
| EBI-HLA | B*3505 | |
| EBI-HLA | B*3506 | |
| EBI-HLA | B*3507 | |
| EBI-HLA | B*3508 | Template:PDB2, Template:PDB2 |
| EBI-HLA | B*3509 | |
| EBI-HLA | B*3510 | |
| EBI-HLA | B*3511 | |
| EBI-HLA | B*3512 | |
| Locus | chr.6 6p21.31 | |
HLA-B35 (B35) is an HLA-B serotype. The serotype identifies the more common HLA-B*35 gene products.[1] B35 is one of the largest B serotype groups, it currently has 97 known nucleotide variants and 86 polypeptide isoforms. (For terminology help see: HLA-serotype tutorial). This variant is particularly susceptible to HIV infection.
Serotype
| B*35 | B35 | Sample | |
| allele | % | % | size (N) |
| 3501 | 98 | 2023 | |
| 3502 | 72 | 1013 | |
| 3503 | 94 | 1226 | |
| 3504 | 100 | 26 | |
| 3505 | 94 | 231 | |
| 3506 | 79 | 10 | |
| 3508 | 91 | 349 | |
| 3509 | 68 | 3 | |
| 3510 | 75 | 12 | |
| 3511 | 67 | 17 | |
| 3512 | 78 | 422 | |
| 3514 | 79 | 29 | |
| 3520 | 42 | 23 |
References
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