HLA-A80

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HLA-A80 (A80) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α80 subset of HLA-A α-chains. For A80, the alpha "A" chain are encoded by the HLA-A<templatestyles src="Template:Color/styles.css" />*80 allele group and the β-chain are encoded by B2M locus.[1] This group currently is dominated by A*8001. A80 and A<templatestyles src="Template:Color/styles.css" />*80 are almost synonymous in meaning.

Script error: No such module "labelled list hatnote". A80 is more common in West Central Africa. A80 is the least common HLA-A allele group.

Serotype

A80 recognition of some HLA A*80 gene products[2]
A*80 A80 A<templatestyles src="Template:Color/styles.css" />10 Sample
allele % % size (N)
*8001 36 <templatestyles src="Template:Color/styles.css" />10 505

A80 HLA-A80 typing is poor. Most typing is done with SSP-PCR. Most of 8001 are detected with "Blank" serotype..

Distribution

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Further reading

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References

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  1. Script error: No such module "Citation/CS1".
  2. Allele Query Form IMGT/HLA - European Bioinformatics Institute

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