HIP2
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Template:Short description Template:Infobox gene Ubiquitin-conjugating enzyme E2 K is a protein that in humans is encoded by the UBE2K gene.[1][2][3]
The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.[3]
Interactions
HIP2 has been shown to interact with Huntingtin[1][4] and RNF2.[5]
References
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Further reading
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