HCP5

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The gene known as HCP5 (HLA Complex P5) is a human endogenous retrovirus, meaning that it is a fossil of an ancient virus that at one time infected people, but has now become an integral part of the human genome.[1]

One variation of HCP5 appears to provide some delay or resistance to the development of AIDS when a person is infected with HIV. This variation of HCP5 frequently occurs in conjunction with a particular version of an immune system gene called HLA-B.[1]

HCP5 has been reported to become upregulated after human papillomavirus infection and may promote the development of cervical cancer.[2][3]

Notes and references

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  1. a b AIDS Abated, B. Vastag, Science News Vol.172 No.3, 21 July 2007
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