Glucarate dehydratase

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Template:Infobox enzyme The enzyme glucarate dehydratase (Template:EnzExplorer) catalyzes the chemical reaction

D-glucarate 5-dehydro-4-deoxy-D-glucarate + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-glucarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming). Other names in common use include D-glucarate dehydratase, and D-glucarate hydro-lyase. This enzyme participates in ascorbate and aldarate metabolism.

Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1BQG, 1EC7, 1EC8, 1EC9, 1ECQ, 1JCT, and 1JDF.

References

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