Globoidnan A
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Globoidnan A is a lignan found in Eucalyptus globoidea, a tree native to Australia.
The molecule has been found to weakly inhibit the action of HIV integrase (IC50 = 0.64 μM) in vitro.[1] HIV integrase is an enzyme which is responsible for the introduction of HIV viral DNA into a host's cellular DNA. It is not known that globoidnan A inhibits the action of other retroviral integrases.
References
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