George Rieveschl

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George Rieveschl (January 9, 1916[1] – September 27, 2007) was an American chemist and professor. He was the inventor of the popular antihistamine diphenhydramine (Benadryl), which he first made while searching for potential muscle relaxant drugs.[1]

Early life and education

Born in Arlington Heights, Ohio, Rieveschl was the son of George and Alma Hoffling Rieveschl.[1] He initially attended the Ohio Mechanics Institute, graduating in 1933, before earning bachelors, masters, and PhD degrees in chemistry[2] at the University of Cincinnati (UC).[1]

Career

After receiving his PhD in 1940, Rieveschl returned to the University of Cincinnati where he served as a professor of chemical engineering, and later a professor of materials science. At the university, he led a research program searching for potential muscle relaxant drugs.[1] In 1943, one of his students, Fred Huber, synthesized diphenhydramine. Rieveschl worked with Parke-Davis to test the compound, and the company licensed the patent from him. In 1947 Parke-Davis hired him as their director of research. While he was there, he led the development of a similar drug, orphenadrine.[3]

Rieveschl remained active in the Cincinnati-area science and arts community until his death at age 91 from pneumonia. He had contributed an estimated $10 million to his alma mater, according to a UC spokeswoman.[1]

The main life sciences building on the campus of the University of Cincinnati is named for Rieveschl.[2]

References

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