GSPT2

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Template:Short description Template:Cs1 config Template:Infobox gene Eukaryotic peptide chain release factor GTP-binding subunit ERF3B is an enzyme that in humans is encoded by the GSPT2 gene.[1][2]

GSPT2 is closely related to GSPT1 (MIM 139259), a GTP-binding protein that plays an essential role at the G1- to S-phase transition of the cell cycle in yeast and human cells. GSPT1 is a positive regulator of translational accuracy and, in a binary complex with eRF1 (MIM 600285), functions as a polypeptide chain release factor.[supplied by OMIM][2]

Interactions

GSPT2 has been shown to interact with PABPC1.[3]

References

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Further reading

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External links


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