GRHPR

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Template:Short description Template:Infobox gene Glyoxylate reductase/hydroxypyruvate reductase is an enzyme that in humans is encoded by the GRHPR gene.[1][2][3]

This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene.[3] GRHPR mutation analysis needs to pay attention to primer design, because allele dropout can cause false-positive result.[4]

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