Furethidine
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Furethidine[1][2][3] is a 4-phenylpiperidine derivative that is related to the clinically used opioid analgesic drug pethidine (meperidine),[4] but with around 25x higher potency.[5] According to another source, Furethidine is 500/30 = 16.7 x the potency of pethidine (table VII).[6][7]
Furethidine is not currently used in medicine and is a Class A/Schedule I drug which is controlled under UN drug conventions. It has similar effects to other opioid derivatives, such as analgesia, sedation, nausea and respiratory depression.[8] In the United States it is a Schedule I Narcotic controlled substance with the ACSCN of 9626.[9]
References
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- ↑ <templatestyles src="Citation/styles.css"/>Template:Citation/make link, Frearson PM, Stern ES, "Novel piperidine compounds and their production", published Script error: No such module "auto date formatter"., assigned to J F Macfarlan & Co LtdScript error: No such module "Check for unknown parameters".
- ↑ Frearson Peter Marshall; Stern Edward Severin, <templatestyles src="Citation/styles.css"/>Template:Citation/make linkScript error: No such module "Check for unknown parameters". (1967 to Glaxo Lab Ltd).
- ↑ Script error: No such module "Citation/CS1".
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- ↑ Casy AF, Parfitt RY. Opioid analgesics, chemistry and receptors. 1986, Plenum Press, New York. pp 234-235. Template:ISBN
- ↑ Blair, A. M. J. N.; Stephenson, R. P. (1960). "ANALGESIC ACTION OF ETHYL 4-PHENYLPIPERIDINE-4-CARBOXYLATES WITH OXYGENATED 1-SUBSTITUENTS". British Journal of Pharmacology and Chemotherapy. 15 (2): 247–253. doi:10.1111/j.1476-5381.1960.tb01239.x.
- ↑ Lister, R. E. (1960). "PHARMACOLOGICAL ACTIONS OF TWO NEW PETHIDINE ANALOGUES". British Journal of Pharmacology and Chemotherapy. 15 (2): 254–259. doi:10.1111/j.1476-5381.1960.tb01240.x.
- ↑ Script error: No such module "Citation/CS1".
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External links
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