Formiminoglutamic acid
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Formiminoglutamic acid (FIGLU; conjugate base, formiminoglutamate) is an intermediate in the catabolism of L-histidine to L-glutamic acid. It thus is also a biomarker for intracellular levels of folate. The FIGLU test is used to identify vitamin B₁₂ deficiency, folate deficiency, and liver failure or liver disease.[1][2] It is elevated with folate trapping, where it is accompanied by decreased methylmalonic acid, increased folate and a decrease in homocysteine.[3]
See also
- Formiminotransferase cyclodeaminase
- Glutamate-1-semialdehyde
- Glutamic acid
- Imidazol-4-one-5-propionic acid
References
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