Fluacizine

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Fluacizine, sold under the brand name Phtorazisin, is a tricyclic antidepressant (TCA) of the phenothiazine group which is or was marketed in Russia.[1][2][3] Unlike other phenothiazines, fluacizine is not an antipsychotic, and can actually reverse catalepsy and extrapyramidal symptoms induced by antidopaminergic agents like antipsychotics, reserpine, and tetrabenazine as well as potentiate amphetamine-induced stereotypy.[3] It is known to act as a norepinephrine reuptake inhibitor, antihistamine, and anticholinergic.[4][5][6][7][3] The drug was developed in the 1960s and was marketed in the 1970s.[1][4] It is the trifluoromethyl analogue of chloracizine.[7]

See also

References

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