EDMA
Template:Short description Script error: No such module "about". Template:Drugbox
3,4-Ethylenedioxy-N-methylamphetamine (EDMA) is an entactogen drug of the methamphetamine class.[1][2] It is an analogue of MDMA where the methylenedioxy ring has been replaced by an ethylenedioxy ring.[1][2] EDMA was first synthesized by Alexander Shulgin.[1] In his book PiHKAL, the dosage is listed as 150–250 mg, and the duration listed as 3–5 hours.[1] According to Shulgin, EDMA produces only mild psychedelic effects consisting of paresthesia, nystagmus, and hypnogogic imagery, with few to no other symptoms.[1]
It has been found that EDMA acts as a non-neurotoxic serotonin releasing agent with moderately diminished potency relative to MDMA, and with negligible effects on dopamine release.[2] However, subsequent research found that EMDA is a serotonin–norepinephrine–dopamine releasing agent (SNDRA) with EC50 values of 117Script error: No such module "String".nM for serotonin release, 325Script error: No such module "String".nM for norepinephrine release, and 597Script error: No such module "String".nM for dopamine release in rat brain synaptosomes.[3] Compared to MDMA, EDMA was about half as potent as a serotonin releaser, 4.5-fold less potent as a norepinephrine releaser, and 8-fold less potent as a dopamine releaser.[3] The activities of the individual enantiomers of EDMA have also been assessed.[3]
See also
- 3,4-Ethylenedioxyamphetamine (EDA)
- 3,4-Ethylenedioxymethcathinone (EDMC)
- 3,4-Ethylidenedioxyamphetamine (EIDA)
- 3,4-Isopropylidenedioxyamphetamine (IDA)
References
<templatestyles src="Reflist/styles.css" />
Script error: No such module "Check for unknown parameters".
External links
Script error: No such module "Navbox". Template:Monoamine releasing agents Script error: No such module "Navbox".