EDF1
Template:Short description Template:Infobox gene Script error: No such module "For". Endothelial differentiation-related factor 1 is a protein that in humans is encoded by the EDF1 gene.[1][2][3]
Function
This gene encodes a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. This protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Two alternatively spliced transcripts which encode distinct proteins have been found for this gene.[3]
Interactions
EDF1 has been shown to interact with:
- Liver X receptor alpha,[4]
- Peroxisome proliferator-activated receptor gamma,[4] and
- TATA binding protein.[4][5][6]
References
<templatestyles src="Reflist/styles.css" />
Script error: No such module "Check for unknown parameters".
Further reading
<templatestyles src="Refbegin/styles.css" />
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".
- Script error: No such module "Citation/CS1".